Anticoagulant therapy in private practice.

نویسنده

  • C A STEPHENS
چکیده

THE DISCOVERY of heparin by McClean in 1916' and the identification of bishydroxycoumerin (Dicumarol) by Link and his co-workers in 1934 as the agent responsible for sweet clover disease in cattle,2 stimulated studies of the clinical use of anticoagulant therapy. The excellent work of Jorpes,3 Zilliacus,4 Barker5" 6 of the Mayo Clinic, and Wright7'8 of New York, and others,9' 10, n has crystallized the indications and contraindications and evaluated the benefits and dangers of this form of therapy in thromboembolic disease. There remain some, however, who question the value of anticoagulant therapy.'2' 13 There are others who maintain that these drugs can be safely and effectively administered only by a few experts supported by a Research Laboratory or a teaching hospital.14' 15 During the past six years in private practice in the community of Tucson, Arizona, the author has successfully administered anticoagulant therapy to 181 patients suffering from thromboembolic conditions. It is the purpose of this report to review this experience and to demonstrate that anticoagulant therapy is a practical, feasible and effective form of therapy in private practice in a small community.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Dabigatran etexilate - A novel oral anticoagulant for bleeding complications

Thromboembolic disease is a common cause of morbidity and mortality. Thrombin plays a key role in thrombotic events and thrombin inhibition represents a therapeutic event for thromboembolic events and has been identified as a target of therapy of its pivotal role in coagulation process. Anticoagulation is a major intervention for the management of arterial and venous thromboembolic events. Dabi...

متن کامل

Thrombophilia, Anticoagulant Therapy, and Pregnancy Outcome in Women with Poor Obstetric History

Background: The role of anticoagulant medications in preventing placental mediated pregnancy complications in patients with and without thrombophilia has not been investigated well. One underlying cause is associated with adverse effects of anticoagulants in pregnancy including teratogenicity, complexities in dosing and management of anticoagulants during pregnancy and labor. We aimed to assess...

متن کامل

Long-term Anticoagulant Therapy.

Experience with long-term anticoagulant therapy during the past seven years has been sumnmarized. This report is based on the records of 227 individuals treated as private or outpatient clinic patients for from four weeks to seven years. Where adequate laboratory facilities are available outpatient long-term therapy may be satisfactorily controlled by physicians familiar with the use of anticoa...

متن کامل

Long-term anticoagulant therapy.

Experience with long-term anticoagulant therapy during the past seven years has been sumnmarized. This report is based on the records of 227 individuals treated as private or outpatient clinic patients for from four weeks to seven years. Where adequate laboratory facilities are available outpatient long-term therapy may be satisfactorily controlled by physicians familiar with the use of anticoa...

متن کامل

Effect of Photodynamic Therapy Using Toluidine Blue on Eikenella corrodens and Aggregatibacter actinomycetemcomitans Biofilms Adhered to Titanium Discs: An In Vitro Study

Background and aim: Antimicrobial photodynamic therapy (aPDT) has been suggested as a novel technique for decontamination of exposed implant surfaces. We aimed to evaluate the effect of aPDT on sandblasted, large-grit, acid-etched (SLA) titanium discs contaminated with Eikenella corrodens (Ec) and Aggregatibacter actinomycetemcomitans (Aa). Materials and methods: In this in-vitro study, twenty...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Circulation

دوره 9 5  شماره 

صفحات  -

تاریخ انتشار 1954